"The Corona crisis has not only put science at the center of public discourse. It has also revealed its vulnerability." In his keynote address at the annual conference of the Deutsches Klima-Konsortium (DKK), Prof. Dr. Jürgen Renn, Director at the Max Planck Institute for the History of Science, explains the challenges science faces in dealing with systemic crises—such as the corona pandemic and climate change—and how it should address them.